BRUNEL UNIVERSITY LONDON

Synthetic Biology

MPhil  |  Placement Year:   No

Research students are welcomed to Brunel as valued members of our thriving, research-intensive community. A research degree provides the opportunity to investigate a topic in depth, and contribute new knowledge to your discipline. An MPhil involves the exploration of a research topic and is typically studied over a shorter period of 1 year for a full-time student and 2 years for a part-time student. MPhil students are required to demonstrate a systematic understanding of knowledge and a critical awareness of current problems and/or new insights informed by the forefront of their discipline, field of study or professional practice.

Research profile
The overall aim of the Synthetic Biology theme is to address major environmental, health and societal challenges by engineering biological systems such that they display functions that do not exist in nature, as well as re-designing existing biological systems so that they perform new functions. Our research focuses on three key areas of activity.

  1. Gene therapy: Some diseases and disorders happen because certain genes work incorrectly or no longer work at all. We are designing therapeutic interventions for human diseases and disorders by developing the technologies to correct defective genes. Our current projects within this area look at vector development for effective gene therapy, assessing and avoiding the risks of gene therapy (genotoxicity) and using the technologies of gene therapy to give new insights into cancer development.
  2. Microbial bioengineering: The most exploitable and engineerable organisms are bacteria, so we want to harness their capacity and diversity to create white technologies –those which cause no harm. Our research uses integrated genomics strategies to direct bacterial engineering for a number of translational applications. We look at possible ways to create novel bacteria –bacteria that can produce clean proteins, for example, or bacteria that can improve the performance of cement. Using bioengineered microbes, we look at ways to degrade environmental pollutants; generate products using alternatives to petrochemicals; and reuse waste biomaterials from biomass and biodiesel manufacture. There are even investigations within our theme into ways of addressing antibiotic resistance in medically important bacteria. We are exploring other areas, and are open to developing new lines of research that will make the best use of the strain and widely applicable tools for strain assessment and development, especially when they are directed at projects that have sustainability as part of what they seek to achieve.
  3. Computer sciences, statistics and maths: We are working on data analysis, bioinformatics, and system modelling to inform synthetic system 30 design and efficient laboratory engineering strategies. These outcomes will support our other strands of research.
Programme description

Research students are welcomed to Brunel as valued members of our thriving, research-intensive community. A research degree provides the opportunity to investigate a topic in depth, and contribute new knowledge to your discipline. An MPhil involves the exploration of a research topic and is typically studied over a shorter period of 1 year for a full-time student and 2 years for a part-time student. MPhil students are required to demonstrate a systematic understanding of knowledge and a critical awareness of current problems and/or new insights informed by the forefront of their discipline, field of study or professional practice.

Research profile
The overall aim of the Synthetic Biology theme is to address major environmental, health and societal challenges by engineering biological systems such that they display functions that do not exist in nature, as well as re-designing existing biological systems so that they perform new functions. Our research focuses on three key areas of activity.

  1. Gene therapy: Some diseases and disorders happen because certain genes work incorrectly or no longer work at all. We are designing therapeutic interventions for human diseases and disorders by developing the technologies to correct defective genes. Our current projects within this area look at vector development for effective gene therapy, assessing and avoiding the risks of gene therapy (genotoxicity) and using the technologies of gene therapy to give new insights into cancer development.
  2. Microbial bioengineering: The most exploitable and engineerable organisms are bacteria, so we want to harness their capacity and diversity to create white technologies –those which cause no harm. Our research uses integrated genomics strategies to direct bacterial engineering for a number of translational applications. We look at possible ways to create novel bacteria –bacteria that can produce clean proteins, for example, or bacteria that can improve the performance of cement. Using bioengineered microbes, we look at ways to degrade environmental pollutants; generate products using alternatives to petrochemicals; and reuse waste biomaterials from biomass and biodiesel manufacture. There are even investigations within our theme into ways of addressing antibiotic resistance in medically important bacteria. We are exploring other areas, and are open to developing new lines of research that will make the best use of the strain and widely applicable tools for strain assessment and development, especially when they are directed at projects that have sustainability as part of what they seek to achieve.
  3. Computer sciences, statistics and maths: We are working on data analysis, bioinformatics, and system modelling to inform synthetic system 30 design and efficient laboratory engineering strategies. These outcomes will support our other strands of research.
Key Modules
Module & Subject
Entry Requirements
  • A minimum score of 60%- 70% or GPA 2.8/4 - 3.4/4. Offers within the grade range are determined by the higher education institution attended.
  • IELTS: 7 (min 6 in all areas)
  • Pearson: 64 (51 in all subscores)
  • BrunELT: 70% (min 60% in all areas)
Foundation Campus
No Foundation
Course Option
Course Duration: 1 year
Course Fee:  18000.00
Course Level:  POSTGRADUATE
Application Deadline 
International Student:   (15,July)
Location
Country:  UNITED KINGDOM
Campus Location:  Brunel University London, Kingston Lane Uxbridge, Middlesex UB8 3PH
Intake Deadline
SEPTEMBER